Effectiveness of Self-Help Group Support in Enhancing Medication Adherence and Quality of Life (QoL) Among Patients with Tuberculosis (TB): A Systematic Review

Iis Puspitasari; Henny Permatasari; Astuti Yuni Nursasi; Widyatuti Widyatuti

doi:10.25311/keskom.Vol11.Iss3.2408

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Effectiveness of Self-Help Group Support in Enhancing Medication Adherence and Quality of Life (QoL) Among Patients with Tuberculosis (TB): A Systematic Review

Iis Puspitasari ¹

, Henny Permatasari ²

, Astuti Yuni Nursasi ²

, Widyatuti Widyatuti ²

¹ Master of Nursing Program Student, Faculty of Nursing, University of Indonesia

² Department of Community Health Nursing, Faculty of Nursing, University of Indonesia

Published 2025-12-30

Vol. 11 No. 3 (2025) PAGES 666-677

DOI 10.25311/keskom.Vol11.Iss3.2408

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Abstract

Tuberculosis (TB) remains a major global health challenge, especially in countries with high disease burdens like Indonesia. Treatment non-adherence and reduced quality of life among TB patients continue to undermine control efforts. This systematic review seeks to explore how self-help group (SHG) interventions contribute to enhancing medication adherence and improving the quality of life (QoL) among individuals living with TB. A systematic review was followed the 2020 PRISMA guidelines. Comprehensive searches were performed across PubMed, Science Direct, ProQuest, Scopus, and Google Scholar using the PICO framework. Studies of various designs (RCTs, cohort, quasi-experimental, and cross-sectional) involving TB patients receiving SHG interventions were included. Eight eligible studies were critically appraised using the JBI checklist. Despite differences in design, participants, and SHG approaches such as patient education, motivation, emotional support, behavioral empowerment, and digital integration the studies consistently showed improvements in medication adherence and quality of life, supported by generally strong methodological quality. The findings highlight the importance of structured SHG models in nursing practice, supporting the development of community-based interventions and protocols that enhance TB treatment outcomes and patient well-being. Future studies should prioritize robust RCTs with diverse populations and long-term follow-up, including hybrid models that integrate digital technologies to ensure sustainable implementation in high-burden settings.

References

1

[1] Adane, K., Spigt, M., Winkens, B., & Dinant, G. J. (2021). Tuberculosis case detection by trained inmate peer educators in a resource-limited prison setting in Ethiopia: a cluster-randomised trial. The Lancet Global Health, 7(4), e482– e491. https://doi.org/10.1016/S2214-109X(18)30477-7

2

[2] Akeju, O. O., Wright, S. C. D., & Maja, T. M. (2017). Lived experience of patients on tuberculosis treatment in Tshwane, Gauteng province. Health SA Gesondheid, 22, 259–267. https://doi.org/10.1016/j.hsag.2017.03.001

3

[3] Barker, T. H., Hasanoff, S., Aromataris, E., Stone, J. C., Leonardi-Bee, J., Sears, K., Habibi, N., Klugar, M., Tufanaru, C., Moola, S., Liu, X. L., & Munn, Z. (2025). The revised JBI critical appraisal tool for the assessment of risk of bias for cohort studies. JBI Evidence Synthesis, 23(3), 441-453. https://doi.org/10.11124/JBIES-24-00103

4

[4] Bonia, B. 2019. Role of self help groups (SHGs) in poverty eradication: Special reference with two villages of Lakhimpur District of Assam. International Journal of Scientific and Technology Research. ISSN 2277-8616

5

[5] Borkman, T. 2023. Self-help and mutual-aid groups for people with mental health, addiction, and other behavioral health conditions. Encyclopedia of Mental Health, Third Edition: Volume 1-3

6

[6] Depkes RI. (2023). Laporan Program Penanggulangan Tuberkulosis Tahun 2022. Depkes RI, 1–147. https://tbindonesia.or.id/pustaka_tbc/laporan- tahunan-program-tbc-2021/

7

[7] Dixit, K., Rai, B., Aryal, T. P., de Siqueira-Filha, N. T., Dhital, R., Sah, M. K., Pandit, R. N., Majhi, G., Paudel, P. R., Levy, J. W., van Rest, J., Gurung, S. C., Mishra, G., Lönnroth, K., Squire, S. B., Annerstedt, K. S., Bonnett, L., Fuady, A., Caws, M., & Wingfield, T. (2024). Stigma, depression, and quality of life among people with pulmonary tuberculosis diagnosed through active and passive case finding in Nepal: a prospective cohort study. BMC Global and Public Health, 2(1). https://doi.org/10.1186/s44263-024-00049-2

8

[8] Gurusinga, R., Afrizal, A., Bachtiar, A., Firdawati, F., Machmud, R., Burhan, E., Jendrius, J., & Semiarty, R. (2024). The relationship between family support and treatment adherence in patients with tuberculosis in Deli Serdang Regency 2022: A cross-sectional study. Nursing and Midwifery Studies, 13(3), 1–10. 10.48307/nms.2024.441017.1351

9

[9] Joshi, D., Sthapit, R., & Brouwer, M. (2022). Peer-led active tuberculosis case-finding among people living with HIV: Lessons from Nepal. Bull World Health Organ, 95(2), 135–139. https://doi.org/10.2471/BLT.16.179119

10

[10] Kemenkes RI. (2020). Temukan TB Obati Sampai Sembuh Penatalaksanaan Tuberkulosis Resisten Obat di Indonesia.

11

[11] Kemenkes RI. (2024). Profil Kesehatan Indonesia 2023. In Kementerian Kesehatan RI.

12

[12] Latha, P., Krishnamurthy, S., & Kumar, S. (2020). Impact of Self-help Groups on Medication Adherence and Quality of Life among Tuberculosis Patients in South India. Journal of Health Research, 34(2), 155-163. https://doi.org/10.1108/JHR-01-2020-0214

13

[13] Mantouw, F., & Widyowati, A. (2024). Optimizing Drug Adherence and QoL of Pulmonary Tuberculosis Patients through Structured Health Education Based on Peer Group Support. 6(2), 324–338. https://doi.org/10.55018/janh.v6i2.239

14

[14] Nursasi, A. Y., Rohana, I. G. A. P. D., Rachmawati, U., & Mulyana, R. (2022). Improved completing- treatment support among tuberculosis support group members through the CERMAT (Smart Against TB Transmission) program. Journal of Community Empowerment for Health, 5(1), 39. https://doi.org/10.22146/jcoemph.66457

15

[15] Ozaltun, S. C., & Akin, L. (2024). An Evaluation of Medication Adherence in New Tuberculosis Cases in Ankara: A Prospective Cohort Study. Healthcare (Switzerland), 12(23). https://doi.org/10.3390/healthcare12232353

16

[16] Park, S., Moon, N., Oh, B., Park, M., Kang, K., Sentissi, I., & Bae, S. H. (2021). Improving treatment adherence with integrated patient management for TB patients in Morocco. International Journal of Environmental Research and Public Health, 18(19). https://doi.org/10.3390/ijerph18199991

17

[17] Potty, R. S., Kumarasamy, K., Munjattu, J. F., Reddy, R. C., Adepu, R., Singarajipura, A., Lakkappa, M. H., Swamickan, R., Shah, A., Panibatla, V., & Washington, R. (2023). Tuberculosis treatment outcomes and patient support groups, southern India. Bulletin of the World Health Organization, 101(1), 28-35A. https://doi.org/10.2471/BLT.22.288237

18

[18] Storvig E, Harstad I, Ehrnström B, Iversen VC. (2024). Beyond the diagnosis of drug-resistant Tuberculosis in Norway: patients' experiences before, during and after treatment. BMC Public Health. PMID: 38971760; PMCID: PMC11227233. DOI: 10.1186/s12889-024-19342-8

19

[19] Syamsir, S. B., Permatasari, H., & Setiawan, A. (2023). Experiences of Patients with Tuberculosis Who Underwent Completed TB Treatment during the COVID-19 Pandemic in Indonesia: A Qualitative Study. International Journal of Community Based Nursing and Midwifery, 11(4), 226–236. https://doi.org/10.30476/ijcbnm.2023.98768.22 57

20

[20] Thirarattanasunthon, P., Wongrith, P., Dadras, O., & Kabmuangpak, S. (2023). The Determinants of Treatment Delay and Quality of Life among the Newly Diagnosed Pulmonary Tuberculosis Patients in Northeastern Thailand: A Cross- Sectional Study. In Infectious Disorders - Drug Targets (Vol. 23, Issue 2, pp. 81–88). https://doi.org/http://dx.doi.org/10.2174/187152 6522666220818142651

21

[21] Wahyudi, D. (2021). Pengaruh Health Coaching pada Self Help Group terhadap Efikasi Diri dan Kepatuhan Program Pengobatan Pasien Tuberkulosis Paru di Kota Sukabumi. 12(April), 34–39. DOI: http://dx.doi.org/10.33846/sf12nk214

22

[22] Wei, X., Hicks, J. P., Zhang, Z., Haldane, V., Pasang, P., Li, L., Yin, T., Zhang, B., Li, Y., Pan, Q., Liu, X., Walley, J., & Hu, J. (2024). Effectiveness of a comprehensive package based on electronic medication monitors at improving treatment outcomes among tuberculosis patients in Tibet: a multicentre randomised controlled trial. The Lancet, 403(10430), 913–923. https://doi.org/10.1016/S0140-6736(23)02270-5

23

[23] World Health Organization. (2024). Global Tuberculosis Report 2024. Geneva: WHO.

24

[24] World Health Organization. (2023). Global Tuberculosis Report 2023. Geneva: WHO

25

[25] World Health Organization. (2021). Tuberculosis: Key Facts. Retrievedfrom https://www.who.int/news-room/fact- sheets/detail/tuberculosis

26

[26] Yadav, R. K., Kaphle, H. P., Yadav, D. K., Marahatta, S. B., Shah, N. P., Baral, S., Khatri, E., & Ojha, R. (2021). Health related quality of life and associated factors with medication adherence among tuberculosis patients in selected districts of Gandaki Province of Nepal. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 23, 100235. https://doi.org/10.1016/j.jctube.2021.100235

Effectiveness of Self-Help Group Support in Enhancing Medication Adherence and Quality of Life (QoL) Among Patients with Tuberculosis (TB): A Systematic Review

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Effectiveness of Self-Help Group Support in Enhancing Medication Adherence and Quality of Life (QoL) Among Patients with Tuberculosis (TB): A Systematic Review

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