Correlation of Adherence to Antiretroviral Therapy With Nutritional Status and CD4 Level Among HIV/AIDS Children
DOI:
https://doi.org/10.25311/keskom.Vol8.Iss2.1097Abstract
Children living with Human Immunodeficiency Virus (HIV) face many challenges, one of which is taking antiretroviral (ART) every day for life to reduce the amount of virus. This study aims to determine the relationship between ART adherence with nutritional status and CD4 in children with HIV/AIDS at RSPI Prof. Dr. Sulianti Saroso. This study was quantitative research with cross sectional design. Samples of all HIV/AIDS child patients with ART treatment and taking ARV drugs at RSPI Prof. Dr. Sulianti Saroso totaling 56 people in 2021 were taken using a total sampling technique. Secondary data sources in this study were obtained from reports of Pokja HIV/AIDS and medical records, data analysis used chi square test (univariate and bivariate data). The results showed that of the 56 respondents, most of them 48 (85.7%) adhered to ART treatment, 43 (76.8%) had good nutritional status, 46 (82.1%) were in good CD4 category (> 500 cells/mm3). There is a relationship between adherence to ART treatment with nutritional status (p value = 0.012 < alpha 5%). There was a relationship between ART treatment adherence and CD4 cell count (p value = 0.003 < alpha 5%). ART adherence is related to nutritional status and CD4 cell count in HIV/AIDS children.
Downloads
References
Akahara, C. et al. (2017) ‘Assessment of Antiretroviral Treatment Adherence among Children Attending Care at a Tertiary Hospital in Southeastern Nigeria’, Journal of Tropical Medecine, 2017(4).
Alessandra Bick, M., Sergio Ceretta, P. and De Paula, C. C. (2019) ‘Feeding of hiv-exposed children in a city in south of Brazil: Family capability, clinical and social conditions’, Revista Brasileira de Saude Materno Infantil, 19(4), pp. 999–1010. doi: 10.1590/1806-93042019000400015.
Almatsier (2019) Prinsip Dasar Ilmu Gizi. Jakarta: PT. Gramedia Pustaka Utama.
Amelia, E. R. (2021) ‘Hubungan Status Gizi Terhadap Kematian Anak HIV/AIDS’, Jurnal Medika Hutama, 02(04), pp. 2016–2019.
Ayu, I. et al. (2017) ‘Tingkat Kepatuhan Mengkonsumsi Obat Antiretroviral Dengan Jumlah Cd4 Pada Pasien Hiv Aids Di Klinik Vct Rsup Sanglah Dalam Periode September – November 2014’, E-Jurnal Medika, 6(1), pp. 1–6.
Boettiger, D. C. et al. (2016) ‘Antiretroviral Therapy in Severely Malnourished, HIV-infected Children in Asia’, The Pediatric infectious disease journal, 35(5), pp. e144–e151. doi: 10.1097/INF.0000000000001074.
Djoerban, Z. (2014) Buku Ajar Ilmu Penyakit Dalam (VI). Jakarta: Interna Publishing.
Haryatiningsih, A. et al. (2017) ‘Hubungan Lamanya Terapi ARV dengan Kepatuhan Minum Obat pada Anak HIV di Klinik Teratai Adherence in Children with HIV’, Jurnal Sistem Kesehatan, 3(2), pp. 80–83.
Hidayati, N. R. and Pandanwangi, S. (2018) ‘Hubungan tingkat kepatuhan penggunaan antiretroviral terhadap jumlah sel cd4 pasien hiv/aids rsud gunungjati cirebon’, Farmasains, 5(2), pp. 55–60.
Indrawanti, R. et al. (2021) ‘Status gizi dan gambaran klinis penyakit pada pasien HIV anak awal terdiagnosis’, Jurnal Gizi Klinik Indonesia, 17(3), p. 125. doi: 10.22146/ijcn.62154.
Kaplan, J. E. (2021) How CD4 counts help treat HIV and AIDS, 15 Juni.
Karyadi, T. H. (2017) ‘Keberhasilan Pengobatan Antiretroviral ( ARV )’, JUrnal Penyakit Dalam Indonesia, 4(1), pp. 2–4.
Kementerian Kesehatan Republik Indonesia (2014) Pedoman Penerapan Terapi HIV Pada Anak. Edited by S. dr. Nia Kurniati. Jakarta.
Kementerian Kesehatan Republik Indonesia (2019) ‘Keputusan Menteri Kesehatan Republik Indonesia Nomor HK.01.07/MENKES/90/2019 Tentang Pedoman Pelayanan Nasional KedokteranTata Laksana HIV’.
Kendre, G. M. et al. (2017) ‘Adherence to antiretroviral therapy and factors affecting adherence among paediatric HIV patients Adherence to antiretroviral therapy and factors affecting adherence among paediatric HIV patients’, International Journal of Contemporary Pediatrics, 4(6). doi: 10.18203/2349-3291.ijcp20174154.
Kim, S. H. et al. (2014) ‘Adherence to antiretroviral therapy in adolescents living with HIV: Systematic review and meta-analysis’, Aids, 28(13), pp. 1945–1956. doi: 10.1097/QAD.0000000000000316.
Nuraidah and Murtiani, F. (2020) ‘Kepatuhan Minum ARV pada Anak dengan HIV Adherence to Taking ARVs in Children with HIV’, The Indonesian Journal of Infectious Disease, 6(2).
Nuraidah, N. and Murtiani, F. (2020) ‘Kepatuhan Minum ARV pada Anak dengan HIV’, The Indonesian Journal of Infectious Diseases, 6(2), p. 9. doi: 10.32667/ijid.v6i2.107.
Oumer, A., Kubsa, M. E. and Mekonnen, B. A. (2019) ‘Malnutrition as predictor of survival from anti-retroviral treatment among children living with HIV/AIDS in Southwest Ethiopia: survival analysis’, BMC Pediatrics, 19(1), p. 474. doi: 10.1186/s12887-019-1823-x.
Rakesh Lodha, S. K. (2015) ‘Health & Nutritional Status of HIV Infected Children’, Indian Journal of Medical Research.
Rihaliza, Murni, A. W. and Alfitri (2019) ‘Hubungan Kepatuhan Minum Obat dan Jumlah CD4 Terhadap Kualitas Hidup Orang dengan HIV AIDS di Poliklinik Voluntary Counseling and Testing RSUP Dr M Djamil Padang’, Jurnal Kesehatan Andalas, 8(4), pp. 162–167.
Rivera, D. M. and Russell W Steele, M. (2020) ‘Pediatric HIV Infection’. Medscape.
Swetha GK , Hemalatha R, Prasad UV, Murali V, Damayanti K, B. V. (2015) ‘Health & nutritional status of HIV infected children in Hyderabad, India’, Indian J Med Res. doi: 10.4103/0971-5916.154494.
Syarifah, Y., Rahmatini and Bahar, E. (2020) ‘Artikel Penelitian Gambaran Pemberian Regimen Antiretroviral pada Pasien’, Jurnal Kesehatan Andalas, 9(Supplement 1), pp. 147–155.
Wadunde, I. et al. (2018) ‘Factors associated with adherence to antiretroviral therapy among HIV infected children in Kabale district , Uganda : a cross sectional study’, BMC Research Notes, 11(466), pp. 1–6. doi: 10.1186/s13104-018-3575-3.
World Health Organization (WHO) (2021) ‘AIDS treatment for Children’.
Zubay, B. et al. (2015) ‘Adherence to Highly Active Antiretroviral Therapy among HIV-Infected Children in Kano , Nigeria’, Journal of Human Virology & Retrovirology, 2(2). doi: 10.15406/jhvrv.2015.02.00033.
Downloads
Submitted
Accepted
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Jurnal Kesehatan Komunitas
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Copyright @2017. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted non-commercial used, distribution and reproduction in any medium
