Risk factors associated with complications of Type 2 Diabetes Mellitus

Authors

  • Erdaliza Erdaliza Program Pascasarjana, Universitas Hang Tuah Pekanbaru
  • Mitra Mitra Program Pascasarjana, Universitas Hang Tuah Pekanbaru
  • Novita Rany Program Pascasarjana, Universitas Hang Tuah Pekanbaru
  • Yessi Harnani Fakultas Kesehatan, Universitas Hang Tuah Pekanbaru
  • Aldiga Rienarti Abidin Fakultas Kesehatan, Universitas Hang Tuah Pekanbaru

DOI:

https://doi.org/10.25311/keskom.Vol10.Iss3.2039

Keywords:

Diabetes mellitus, kolesterol, komplikasi, kontrol rutin, tekanan darah

Abstract

Type 2 Diabetes Mellitus (T2DM) is a chronic disease with an increasing prevalence in Indonesia and globally. Complications from T2DM have serious impacts on the quality of life for patients. The increase in the number of complications in T2DM patients at Selasih Regional Hospital, Pelalawan Regency, is the main issue in this research. The study aims to identify risk factors associated with complications in T2DM patients at Selasih Regional Hospital, Pelalawan Regency. The research design used is a case-control study with a sample of 400 patients (200 cases and 200 controls). Cases are T2DM patients with complications, while controls are T2DM patients without complications. Case and control samples were taken using a systematic random sampling method. Data were collected from the medical records of Selasih Regional Hospital in 2023. Data analysis was conducted using chi-square tests and multiple logistic regression. The results showed that high cholesterol (OR=206.46), duration of DM (OR=79.62), high blood pressure (OR=22.54), and irregular check-ups (OR=4.43) were significantly associated with T2DM complications. Interventions to control cholesterol and blood pressure and to increase routine check-ups can reduce the risk of T2DM complications. Therefore, there is a need for increased education and health promotion programs from the hospital regarding diabetes management to prevent the occurrence of T2DM complications.

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References

1. Khan MAB, Hashim MJ, King JK, Govender RD. Epidemiology of Type 2 Diabetes - Global Burden of Disease and Forecasted Trends. J Epidemiol Glob Health. 2020;10(1):107–11.

2. Okur I, Taspinar B, Telli Atalay O, Pasali Kilit T, Toru Erbay U, Okur EO. The effects of type 2 diabetes mellitus and its complications on physical and pulmonary functions: A case–control study. Physiother Theory Pract [Internet]. 2020 Aug 2;36(8):916–22. Available from: https://doi.org/10.1080/09593985.2018.1517198

3. Garg P, Duggal N. Type 2 diabetes mellitus, its impact on quality of life and how the disease can be managed-a review. Obes Med [Internet]. 2022;35:100459. Available from: https://www.sciencedirect.com/science/article/pii/S2451847622000719

4. Saputri RD. Komplikasi Sistemik Pada Pasien Diabetes Melitus Tipe 2. J Ilm Kesehat Sandi Husada. 2020;11(1):230–6.

5. Sembiring IS, Rahmawati D, Ramadhan AM. Analisis Efektivitas Biaya dan Minimal Biaya Pasien Diabetes Melitus Tipe 2 di RSUD Abdul Wahab Sjahranie Samarinda Tahun 2019. Proceeding Mulawarman Pharm Conf. 2021;14(3):173–8.

6. Balooch Hasankhani M, Mirzaei H, Karamoozian A. Global trend analysis of diabetes mellitus incidence, mortality, and mortality-to-incidence ratio from 1990 to 2019. Sci Rep [Internet]. 2023;13(1):1–8. Available from: https://doi.org/10.1038/s41598-023-49249-0

7. Indonesia KK. Profil Kesehatan Indonesia 2022. Jakarta: Kementerian Kesehatan RI; 2022.

8. Milita F, Handayani S, Setiaji B. Kejadian Diabetes Mellitus Tipe II pada Lanjut Usia di Indonesia (Analisis Riskesdas 2018). J Kedokt dan Kesehat. 2021;17(1):9.

9. Murtiningsih MK, Pandelaki K, Sedli BP. Gaya Hidup sebagai Faktor Risiko Diabetes Melitus Tipe 2. e-CliniC. 2021;9(2):328–33.

10. Amirah AD, Sumiaty, Ella Andayanie. Hubungan Pola Makan Dengan Kejadian Diabetes Melitus Pada Masyarakat Usia Di Atas 40 Tahun Di Kabupaten Gowa. Wind Public Heal J. 2022;3(3):502–15.

11. Riau DKP. Profil Kesehatan Provinsi Riau 2022. Pekanbaru: Dinas Kesehatan Provinsi Riau; 2022.

12. Molina RT, Ríos García AL, Vergara TA, Florez-Garcia VA, Gutierrez VR, Lozano KF, et al. Predictors of diabetes risk in urban and rural areas in Colombia. Heliyon. 2021;7(1):1–7.

13. Ningrum DK. Kepatuhan Minum Obat pada Penderita Diabetes Melitus Tipe II. Higeia J Public Heal Res Dev. 2020;4(3):493–505.

14. Beyene A, Habte T, Hailu A. Low-Density lipoprotein cholesterol goal achievement and associated factors among type 2 diabetes mellitus patients at Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia: Cross-sectional Study, 2023. Int J Africa Nurs Sci [Internet]. 2024;20(June):100737. Available from: https://doi.org/10.1016/j.ijans.2024.100737

15. Chakraborty S, Verma A, Garg R, Singh J, Verma H. Cardiometabolic Risk Factors Associated With Type 2 Diabetes Mellitus: A Mechanistic Insight. Clin Med Insights Endocrinol Diabetes. 2023;16(1):1–18.

16. Latha VA, Mondu SSD, Dinesh Eshwar M, Polala AR, Nandanavanam S, Dodda S. Dyslipidemia Among Diabetes Mellitus Patients: A Case-Control Study From a Tertiary Care Hospital in South India. Cureus. 2023;15(2):1–7.

17. Bodaghi AB, Ebadi E, Gholami MJ, Azizi R, Shariati A. A decreased level of high-density lipoprotein is a possible risk factor for type 2 diabetes mellitus: A review. Heal Sci Reports. 2023;6(12):1–11.

18. De Rosa S, Arcidiacono B, Chiefari E, Brunetti A, Indolfi C, Foti DP. Type 2 diabetes mellitus and cardiovascular disease: Genetic and epigenetic links. Front Endocrinol (Lausanne). 2018;9(1):1–13.

19. Thiruvoipati T. Peripheral artery disease in patients with diabetes: Epidemiology, mechanisms, and outcomes. World J Diabetes. 2015;6(7):961.

20. Guan H, Tian J, Wang Y, Niu P, Zhang Y, Zhang Y, et al. Advances in secondary prevention mechanisms of macrovascular complications in type 2 diabetes mellitus patients: a comprehensive review. Eur J Med Res [Internet]. 2024;29(1):1–34. Available from: https://doi.org/10.1186/s40001-024-01739-1

21. Deshpande AD, Harris-Hayes M, Schootman M. Epidemiology of Diabetes and Diabetes-Related Complications. Phys Ther. 2008;88(11):1254–64.

22. Soegondo. Penatalaksanaan Diabetes Mellitus Terpadu. Jakarta: Balai Penerbit FKUI; 2017.

23. Yen FS, Wei JCC, Shih YH, Hsu CC, Hwu CM. The Risk of Nephropathy, Retinopathy, and Leg Amputation in Patients With Diabetes and Hypertension: A Nationwide, Population-Based Retrospective Cohort Study. Front Endocrinol (Lausanne). 2021;12(1):1–10.

24. De Faria JBL, Silva KC, Lopes De Faria JM. The contribution of hypertension to diabetic nephropathy and retinopathy: The role of inflammation and oxidative stress. Hypertens Res. 2011;34(4):413–22.

25. Flack JM, Adekola B. Blood pressure and the new ACC/AHA hypertension guidelines. Trends Cardiovasc Med [Internet]. 2020;30(3):160–4. Available from: https://doi.org/10.1016/j.tcm.2019.05.003

26. Kim HJ, Kim K Il. Blood Pressure Target in Type 2 Diabetes Mellitus. Diabetes Metab J. 2022;46(5):667–74.

27. Jia G, Sowers JR. Hypertension in Diabetes: An Update of Basic Mechanisms and Clinical Disease. Hypertension. 2021;78(5):1197–205.

28. Petrie JR, Guzik TJ, Touyz RM. Diabetes, Hypertension, and Cardiovascular Disease: Clinical Insights and Vascular Mechanisms. Can J Cardiol [Internet]. 2018;34(5):575–84. Available from: https://doi.org/10.1016/j.cjca.2017.12.005

29. Vadila A, Izhar MD, Nasution HS. Faktor-Faktor Kejadian Diabetes Melitus Tipe 2 di Puskesmas Putri Ayu. Media Kesehat Politek Kesehat Makassar. 2021;XVI(2):229–37.

30. Sreedevi A, Krishnapillai V, Menon VB, Mathew MM, Nair RR, Pillai GS, et al. Uncontrolled Blood Pressure and Associated Factors Among Persons With Diabetes: A Community Based Study From Kerala, India. Front Public Heal. 2022;9(1):1–7.

31. Naaman SC, Bakris GL. Diabetic Nephropathy: Update on Pillars of Therapy Slowing Progression. Diabetes Care. 2023;46(9):1574–86.

32. Raflin BR Sinaga M, Yensuari Y, Dharma S. Pengaruh Kendali Glukosa Darah, Hipertensi, Dan Dislipidemia Terhadap Komplikasi Retinopati Diabetik Pada Penderita Diabetes Melitus Tipe 2. J Multidisiplin Indones. 2023;2(10):3304–19.

33. Sun B, Huang XS. Painful peripheral neuropathy. Chinese J Contemp Neurol Neurosurg. 2013;13(9):755–9.

34. Rizvi AA. Addressing Hypertension in the Patient with Type 2 Diabetes Mellitus: Pathogenesis, Goals, and Therapeutic Approach. EMJ Diabetes. 2017;5(1):84–92.

35. Tandra H. Segala Sesuatu yang Harus Anda Ketahui tentang Diabetes. Jakarta: Gramedia Pustaka Utama; 2018.

36. Bin Rakhis SA, AlDuwayhis NM, Aleid N, AlBarrak AN, Aloraini AA. Glycemic Control for Type 2 Diabetes Mellitus Patients: A Systematic Review. Cureus. 2022;14(6):6–13.

37. Quraisy CCRSA, Mulyani NS. Faktor-faktor yang Berhubungan dengan Kejadian Fiabetes Mellitus Tipe-II pada Pasien Rawat Jalan. J SAGO Gizi dan Kesehat. 2021;2(2):122.

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Submitted

2024-09-15

Accepted

2024-09-29

Published

2024-12-16

How to Cite

1.
Erdaliza E, Mitra M, Rany N, Harnani Y, Rienarti Abidin A. Risk factors associated with complications of Type 2 Diabetes Mellitus. J Keskom [Internet]. 2024 Dec. 16 [cited 2024 Dec. 21];10(3):534-45. Available from: https://jurnal.htp.ac.id/index.php/keskom/article/view/2039

Issue

Vol. 10 No. 3 (2024): Journal of Community Health

Section

Articles

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