Analysis of Antibiotic use for Covid-19 Patients in the Isolation Room of the Hospital X Tipe D at Malang District

Authors

  • Retno Juwita Sari retno juwita
  • Rika Yulia Fakultas Farmasi Universitas Surabaya, Indonesia
  • Fauna Herawati Fakultas Farmasi Universitas Surabaya, Indonesia

DOI:

https://doi.org/10.25311/keskom.Vol9.Iss2.1268

Keywords:

: COVID-19; DDD/100 patient-day; Kriteria Gyssens; Penggunaan antibiotik

Abstract

COVID-19 cases by the end of 2019 have raised the number of respiratory tract infections; in addition, coinfection during COVID-19 pandemic is associated with disease severity, consequently,causes the number of deaths to surge. The use of antibiotics during the pandemic has evidently improved in a significant way, similar to the increased number of broad-spectrum prescriptions. This phenomenon potentially elevates the number of Antimicrobial Resistance (AMR); therefore, it is necessary to fortify supervision over the use of antibiotics during COVID-19 pandemic. Referring to this, the objective of the study is to evaluate the use of antibiotic during COVID-19 pandemic. This is an observational study conducted on adult subjects with confirmed COVID-19, with moderate to severe level of disease, whose data was collected retrospectively during the period of April 2020 – March 2021. The result confirmed 146 patients were treated as sample of the study, most of whomwere male (53.4%),and female was 46.6%.  The highest age group was 56 – 65 years old by 28.8%. The increase in leukocyte level > 1.000 was 31.5%. 8 (eight) types of antibiotics were used in high frequency, such as, injection levofloxacin antibiotics (50%),while frequently used combination antibioticswere ceftriaxone and levofloxacin (5.5%). Based on quantitative analysis, the total value was 60,54 DDD/100 patient-days, and the value of antibiotic with the highest DDD was levofloxacin 26.51 DDD/100 patient-days. Additionally, the result of analysis on the quality of antibiotics using Gyssens flowchart suggested 36.3% of the given antibiotic were considered as rational (category 0) and 46.6% of the given antibiotics had no indication of usage (category V). Prospective research is needed regarding the use of antibiotics.

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Submitted

2022-07-02

Accepted

2022-10-18

Published

2023-07-31

How to Cite

1.
Sari RJ, Yulia R, Herawati F. Analysis of Antibiotic use for Covid-19 Patients in the Isolation Room of the Hospital X Tipe D at Malang District. J Keskom [Internet]. 2023 Jul. 31 [cited 2024 Apr. 16];9(2):300-4. Available from: https://jurnal.htp.ac.id/index.php/keskom/article/view/1268